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The Journal of Clinical Investigation is the publication of the American Society for Clinical Investigation, an honor society of physician-scientist.

The JCI is a top-tier venue for critical advances in biomedical research. The JCI combines a 2009 Impact Factor of 15.387 with immediate free access to its research articles to produce an ideal home for authors seeking the widest possible audience for their most important work. The journal is headed by Editor in Chief Dr. Laurence A. Turka (Harvard University, Beth Israel Deaconess Medical Center) and an Editorial Board of peer scientists at the University of Pennsylvania whose depth and experience ensures fair and competent peer review. Dr. Ushma Neill serves as the JCI's Executive Editor.

More info here: http://www.jci.org/.